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There are some tendons and a nerve bundle that run through a particular opening on the inside of your wrist (known as the "carpal tunnel"). When something passing through that tunnel gets inflamed, for example by keeping your wrist bent at an unnatural angle for extended periods of time, the nerve can get pinched. This causes pain or numbness that can run from the tips of your index and middle fingers all the way back to your elbow.

If you notice it early and take steps to avoid stressing your wrists (such as wearing wrist braces or improving your posture when working) it can heal, but if you keep overworking your body then it can result in chronic pain that can sometimes even need surgery to relieve.