[Serra Britt]

Originally Posted by nyreen

That's certainly a good thing to keep in mind! I can imagine if you just start up a webcomic, with no backlog, that it'd become quickly overwhelming and stressful. It can also cost you followers right? So that's bad. I figured the weekend would be the best time for me to upload my webcomic as it's when most people are online and free. ^^

This is pretty much the reasoning yes. I suspect long time readers are far more receptive to a hiatus if you've kept a regular update schedule up until then. And for a new webcomic, you're probably attracting a few new readers who will be looking for a reliable update schedule. From what I understand, it's not the frequency of updates that's important, but the reliability of those updates. Reading a webcomic can be a thing done easily on one's own schedule when they know when to expect a page, but can be unpleasant when you don't know when it will be and end up checking every day with more and more disappointment each day.